Benzodiazepine Addiction Treatment
Written By
Updated On : July 31, 2024
Benzodiazepines (benzos) are an extremely common class of drugs that most people will take at some point in life. They’re often prescribed to treat muscle spasms and anxiety or to help with sleep, though some people abuse them for their tranquilizing effects. The latter is dangerous and comes with certain irreversible health risks.
Benzodiazepines (benzos) are prescription medications that relax the body and mind.[1] The relaxation effect is due to heterocyclic organic compounds, which cause the user to enter a timed hypnotic or tranquil state.[2] As a result, they’re commonly prescribed as sedatives or muscle relaxers. Their hypnotic effect is also beneficial in calming overactivity in the mind, which often happens during a bout of anxiety, insomnia, or leading up to a seizure.
The most commonly prescribed benzodiazepines are:[3]
Some benzodiazepines are called short-acting because they’re processed by the body quicker, and the effects don’t last long.[4] Short-acting benzos begin working in as little as 30 to 60 minutes and are most suitable as sedatives in a critical care setting. However, some are also prescribed to treat insomnia.
They include:
According to the Controlled Substance Act (CSA), benzodiazepine is a Schedule IV Controlled Substance.[5] Drugs in this category have a low risk for addiction – when used as prescribed. However, when someone uses prescription benzodiazepines in a fashion other than prescribed, they are at risk of developing a dependency.
This includes the following:
According to Yale researchers, it only takes four weeks for 50% of regular benzo users to develop tolerance and dependency.[6] This action is caused by changes in the brain after extended use.
People who aren’t prescribed benzodiazepines may buy them on the street to mitigate the negative effects of opioids or methamphetamines. Others obtain them illegally to self-treat mental health symptoms associated with Attention-Deficit Hyperactivity Disorder (ADHD) or anxiety. Some people also buy them due to peer pressure.[7]
The problem with illicit benzodiazepines is that they are not regulated. This means no one knows what’s actually in them. They could be synthetic, fake, or adulterated – and adulterated benzodiazepines are especially problematic.[8]
In an attempt to boost sales, street dealers may cut in other illicit drugs, such as opioids, to make benzodiazepines more addictive. However, the user is often unaware of this and may develop an addiction to multiple substances or overdose on the additive.
Although there are multiple causes for the soaring popularity of benzodiazepine use amongst Americans, researchers point to the increasing prevalence of anxiety, benzo mentions in popular music, and drug trafficking as contributing factors.
Anxiety is a feeling of worry, fear, or apprehension that often comes as a reaction to stress. During an anxiety attack, people feel uncomfortable symptoms as a result of the brain’s fight-or-flight reaction.
These symptoms include, but aren’t limited to:
In an attempt to stave off these feelings and avoid the stigmas associated with counseling, people often seek out pharmaceutical recommendations from their physicians or peers. This has led to a significant increase in benzodiazepine prescriptions for adults in the United States. In fact, it’s become the top prescribed drug class for adults with anxiety — a number that’s currently topping 40 million.[9]
The Drug Enforcement Agency stated that a combined 93.4 million prescriptions were written out for alprazolam, lorazepam, clonazepam, diazepam, and temazepam as of August 2023.[10]
Illicit benzodiazepine use has become a socially acceptable phenomenon in the United States, with some rappers and social influencers using their platforms to glorify their use.
Dazed Magazine named Xanax, “The drug that defined the decade and changed rap,” as it appeared in so many song lyrics.[11]
In fact, a genre of rap known as “emo rap” emerged from benzo use, characterized by mumbled lyrics and drug references. It is also common to see rappers posing in pictures with Benzo pills on their tongues or nodding off during live streams and interviews.
Unfortunately, there were also several rappers, most notably Lil Peep and Mac Miller, who died shortly after overdosing on suspected adulterated benzodiazepines.
Over the past decade, Direct-to-Consumer (DTC) pharmaceutical ads began creeping into videos all over YouTube.[12] This increased awareness of the drug’s effects and side effects, leading to increased search traffic from people seeking them out after watching the ad.
The advertisements show working-class individuals with families who “need” the drug to feel “normal.” This approach in direct-to-consumer pharmaceutical ads is problematic, as researchers believe it leads to increased drug requests and costs.
As a result, people who cannot afford the drug may turn to street dealers for a more affordable alternative, which unfortunately often comes with serious risks.
A person who is abusing benzodiazepines will often show outward signs of being under the influence.
These signs include:
People with benzo addiction will display several behavioral issues that include:
Physical signs of benzo addiction include:[13]
When taken at high doses, they can also experience signs of benzodiazepine toxicity, which include:[14]
Benzodiazepines suppress the nervous system by binding to gamma-aminobutyric acid (GABA) receptors in the brain.[15] GABA receptors are responsible for reducing excitability in the brain related to breathing, emotion, memory, and reason. Simultaneously, benzodiazepines inhibit the brain’s ability to regulate pleasure, resulting in a flood of the feel-good chemical dopamine.
When used as prescribed, these effects are mild. They calm overactivity in the brain, allowing the user to relax.
However, after using them for a prolonged time or in an abusive fashion, the body develops tolerance, decreasing GABA activity and increasing excitability. This causes the person to feel anxious, irritable, or wired.
In an attempt to reduce these uncomfortable effects and increase the effects of dopamine, they will use more of the drug, entering into a perpetual cycle of increased doses and decreased effectiveness.
Unfortunately, as this cycle continues, the body becomes acclimated to the presence of benzodiazepines and has trouble adjusting when they aren’t present. This results in withdrawal symptoms that affect the mind and body.
They include:
People who abuse benzodiazepines are also at an increased risk of developing hip fractures and long-term cognitive impairment.
Recovering from benzodiazepine addiction may seem impossible, but with the right support, recovery is achievable.
If you or a loved one has an addiction to benzodiazepines, contact Engage Wellness Acton Together, we can help you determine the most suitable treatment option for your goals and support you on your journey to long-term recovery.
Breaking free from benzodiazepine addiction requires specialized healthcare that addresses both the physical and mental health aspects of recovery. Benzos like Xanax, Klonopin, Ativan, and Valium affect the central nervous system, making withdrawal symptoms potentially life-threatening without proper medical supervision.[16]
Engage Wellness combines evidence-based therapies with comprehensive medical support to address benzodiazepine addiction and withdrawal. Our treatment programs focus on safely tapering medications like Xanax, Klonopin, Ativan, and Valium while treating underlying anxiety disorders and mental health conditions.
Key signs include needing higher doses for the same effect, experiencing anxiety or withdrawal symptoms between doses, and being unable to stop despite wanting to quit.
We accept all commercial insurance plans and TRICARE, making treatment accessible with various coverage options for different levels of care
Stopping benzodiazepines abruptly can cause life-threatening withdrawal symptoms, including seizures, so medical supervision is essential for safe tapering.
[1] Gbemudu, A. (2016, May 2). Benzodiazepines. RxList; RxList. https://www.rxlist.com/benzodiazepines/drug-class.htm on February 13, 2025
[2] Heterocyclic Compound – an overview | ScienceDirect Topics. (n.d.). Www.sciencedirect.com. https://www.sciencedirect.com/topics/chemistry/heterocyclic-compound on February 13, 2025
[3] Longo, L. P., & Johnson, B. (2000). Addiction: Part I. Benzodiazepines—Side Effects, Abuse Risk and Alternatives. American Family Physician, 61(7), 2121–2128. https://www.aafp.org/pubs/afp/issues/2000/0401/p2121.html on February 13, 2025
[4] United States Drug Enforcement Administration. (2022, October). Benzodiazepines. Dea.gov. https://www.dea.gov/factsheets/benzodiazepines on February 13, 2025
[5] Ortiz, N. R., & Preuss, C. V. (2024, February 9). Controlled Substance Act. Nih.gov; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK574544 on February 13, 2025
[6] Chen, J. (2019, December 11). Are Benzodiazepines the New Opioids? Yale Medicine. https://www.yalemedicine.org/news/benzodiazepine-epidemic on February 13, 2025
[7] National Institute of Mental Health. (2024, September). Attention-Deficit/Hyperactivity disorder. Www.nimh.nih.gov; National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/attention-deficit-hyperactivity-disorder-adhd on February 13, 2025
[8] Russell, C., Law, J., Bonn, M., Rehm, J., & Ali, F. (2023). The increase in benzodiazepine-laced drugs and related risks in Canada: The urgent need for effective and sustainable solutions. International Journal of Drug Policy, 111, 103933. https://www.sciencedirect.com/science/article/pii/S0955395922003498 on February 13, 2025
[9] Anxiety Statistics And Facts. (2023, October 19). Forbes Health. https://www.forbes.com/health/mind/anxiety-statistics/ on February 13, 2025
[10] DEA Office of Diversion Control. (2013). BENZODIAZEPINES (Street Names: Benzos, Downers, Nerve Pills, Tranks). https://www.deadiversion.usdoj.gov/drug_chem_info/benzo.pdf on February 13, 2025
[11] Hobbs, T. (2019, December 17). Xanax: the drug that defined the decade and changed rap. Dazed. https://www.dazeddigital.com/music/article/47214/1/xanax-the-drug-that-changed-rap-lil-peep-juice-wrld-end-of-decade on February 13, 2025
[12] Shmerling, R. H. (2022, March 3). Harvard health ad watch: What you should know about direct-to-consumer ads. Harvard Health Blog. https://www.health.harvard.edu/blog/harvard-health-ad-watch-what-you-should-know-about-direct-to-consumer-ads-2019092017848 on February 13, 2025
[13] Brett, J., & Murnion, B. (2015). Management of benzodiazepine misuse and dependence. Australian prescriber, 38(5), 152–155. https://doi.org/10.18773/austprescr.2015.055 on February 13, 2025
[14] Kang, M., Galuska, M. A., & Sassan Ghassemzadeh. (2023, June 26). Benzodiazepine Toxicity. Nih.gov; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK482238/%23 on February 13, 2025
[15] Walters, R. J., Hadley, S. H., Morris, K. D. W., & Amin, J. (2000). Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms. Nature Neuroscience, 3(12), 1274–1281. https://pubmed.ncbi.nlm.nih.gov/11100148/ on February 13, 2025
[16] Cleveland Clinic. (2023, March 1). Benzodiazepines: What they are, uses, side effects & risks. Cleveland Clinic. https://my.clevelandclinic.org/health/treatments/24570-benzodiazepines-benzos on February 12, 2025