Is Methocarbamol Addictive? Understanding the Risks of Muscle Relaxant Addiction
Medically Reviewed By
Written By
Last medically reviewed : March 10, 2025
Updated On : March 10, 2025
Medically Reviewed By
Written By
Last medically reviewed : March 10, 2025
Updated On : March 10, 2025
Many prescription drugs are open to misuse, particularly when individuals don’t understand the risks of taking too much. Painkiller addiction, for example, is on the rise, with the American Medical Association (AMA) reporting that “one-size-fits-all” opioid restriction policies are causing more harm than good, leading to people seeking dangerous alternatives to prescription medication. [1]
Methocarbamol, while sometimes used for pain relief, does not fall into the same category as opioids and doesn’t cause addiction in the same way. However, that doesn’t mean there aren’t risks associated with the misuse of this powerful muscle relaxant. Understanding these risks and the potential outcomes can help you recognize if you or someone you love may be struggling with substance misuse.
Methocarbamol, often sold under the medication brand name Robaxin, is a skeletal muscle relaxant derived from an expectorant called guaifenesin.[2] Guaifenesin works by relaxing various muscle groups in the throat and airways to help treat coughs and related symptoms. Methocarbamol has a similar action but is used for treating pain caused by musculoskeletal conditions or muscle spasms.
A medical professional may prescribe methocarbamol to be taken either orally or via intravenous or intramuscular injection. It’s often prescribed for back pain where other treatments have failed.[3]
Despite its use as a muscle relaxant, methocarbamol doesn’t actually interact directly with muscles. Scientists aren’t sure exactly what causes the relaxation of muscles when someone takes the drug, but the general consensus is that a general sedative effect most likely causes it. Methocarbamol may also block nerve impulses to the brain, stopping the pain response in its tracks. [4]
The main side effect of methocarbamol is closely linked to its sedative effect: drowsiness. Users aged between 18 and 60 who aren’t taking other medications may feel sleepy or experience lightheadedness when they stand up.[5] They may also feel flushed or report lower blood pressure than usual.
Because of its ability to cause drowsiness, it’s recommended that users don’t drink alcohol while taking methocarbamol. The substances can interact, leading to more serious side effects. It’s also important not to drive or operate machinery.
Methocarbamol interacts with other drugs that can also have a sedative effect. These include but aren’t limited to opioids and opiates, antihistamines, and benzodiazepines.
More severe side effects include:[5]
Any of these adverse effects should be immediately reported to a medical professional.
With most addictive prescription drugs, addiction occurs because the body and brain become gradually used to the effects and crave a stronger dose or more frequent applications of the substance. Because methocarbamol doesn’t affect the body or brain in the same way as opioids, there’s less risk of physical addiction to the substance. Users shouldn’t need to constantly upgrade the volume of methocarbamol to get the same feeling. Also, there’s no euphoria or “high” to chase, as this drug has a primarily sedative effect.
However, that doesn’t prevent people from misusing methocarbamol.[6] Some people enjoy the sedative effects of this type of muscle relaxant and may take more than needed to gain a deeper level of sedation. They may also mix methocarbamol with other substances as a form of recreational experimentation. The habit-forming nature of methocarbamol use is largely psychological or connected to other, more addictive substances. So, even though methocarbamol itself has no withdrawal symptoms, users may associate its use with the cravings linked to alcohol or opioids.
Some people may become so used to the feelings provided by methocarbamol that they simply don’t want to live without it, even if a doctor recommends they switch to another drug or lower their dosage. Others may take more methocarbamol than recommended because other drugs, such as opioid-based painkillers, are restricted or not as effective as they used to be.
Taking any type of prescription drug carries risks when users don’t follow the medical advice of their physician. As stated, there are serious side effects associated with methocarbamol use, and taking it more frequently or at higher doses could increase the risks of experiencing these side effects.
There hasn’t been much research into the effects of methocarbamol overdose, so there isn’t a set dosage that’s classed as acutely toxic. However, some of the symptoms associated with overdose include:[7]
Overdose cases typically occur when taking methocarbamol with alcohol or other substances, particularly other central nervous system depressants. [8]
Knowing that this muscle relaxant can lead to seizures, coma, and death may be alarming to those who use this substance regularly. [5] However, if you follow the instructions of your physician, there’s no reason why you should be at greater risk unless you regularly take your methocarbamol with other substances. If you need to do this — for example, if you take strong painkillers for another condition — discuss the possible ramifications with your doctor.
Recognizing the signs of methocarbamol addiction can be tricky, as the drug doesn’t cause cravings in the conventional sense. The following signs may indicate you’re starting to struggle with addiction:
This list is not exhaustive. Any change in behavior or character associated with your use of a prescription drug could indicate a pathway to addiction.
The earlier you seek help for any drug abuse or misuse, the faster your pathway to recovery can be. Of course, it’s never too late to look for support. Holistic addiction treatment can help you understand what aspects of your life have led to substance misuse and support your mind, body, and psyche as you work toward recovery.
Addiction is rarely a standalone condition. Substance misuse can lead to many mental health difficulties, including anxiety and depression. An effective treatment program will normally assess and treat these conditions with therapies, including one-on-one and group sessions. Group sessions are impactful because they let you know you’re not alone. You’re empowered to talk about your experiences with others who may have been on a similar journey. This type of group work can help you forge new connections, which can bolster your recovery strategy.
One-on-one therapies empower medical professionals to create completely bespoke plans tailored to your needs. Talking therapies such as cognitive behavioral therapy (CBT) are useful, as they help you to reframe your thoughts and feelings. Where trauma is an aspect of addiction, eye movement desensitization and reprocessing (EMDR) therapy may be employed. This type of therapy can calm the parts of the brain associated with trauma recall, helping reduce the impact of these types of memories.
Methocarbamol dependence and misuse can also cause physical health problems. If you’ve experienced seizures, for example, you might need physical therapy to help recover from the effects of these. A truly holistic approach ensures you have the opportunity to keep active in a way that’s suitable for you and your mobility levels. You’ll also gain the chance to interact with creative pursuits, keeping the mind active while satisfying the psyche.
Taking a muscle relaxant safely means always following the advice of your healthcare provider. The primary risk of ignoring your doctor’s recommendations is that you’ll take too much or too little. You may end up in pain when you don’t need to be or, conversely, get used to the stronger sedative effect of the higher dose.
Ensure safe methocarbamol use with these tips:
If you struggle to follow these tips or know someone who is having problems with potential prescription drug misuse, consider contacting a professional for compassionate yet objective support.
The most important thing to know about any type of prescription drug misuse concern is that you are not alone. Whether you are worried for yourself or someone else, there are support functions available to help you overcome addiction. At Engage Wellness Acton, Massachusetts, we provide day treatment services as well as intensive outpatient treatment programs, so you’ll always find the program that suits you and your needs. We also focus on relapse prevention and family therapy to ensure that you or your loved one has the long-term support they need to move away from substance reliance.
For more information, contact a member of our team and start your recovery journey today.
Methocarbamol creates a drowsy, sedative effect which is stronger when mixed with alcohol and painkillers. While methocarbamol or Robaxin addiction is rare, methocarbamol abuse can occur when taking too much of the drug or taking it too frequently.
Muscle relaxants aren’t normally addictive, but they are still open to misuse. When mixed with alcohol and other CNS depressants, such as sleeping pills, they may cause serious physical and mental problems. Users may need to fully detox before they can take the relaxants safely again.
The most common side effects of methocarbamol are drowsiness and dizziness. However, there are some rarer side effects, including stomach pain, rapid heart rate, and seizures.
[1] American Medical Association (November 2024) – Overdose Epidemic Report 2024 – State Policies: Support individualized pain care. Retrieved from https://end-overdose-epidemic.org/wp-content/uploads/2024/11/24-1177083-Advocacy-2024-Overdose-Report_DIGITAL-2.pdf on 2025, January 11.
[2] David B Bylund; Reference Module in Biomedical Sciences (2017) – Methocarbamol – Introduction. Retrieved from https://www.sciencedirect.com/topics/neuroscience/methocarbamol on 2025, January 11.
[3] Steven D. Waldman MD, JD. Pain Review – Methocarbamol (Robaxin). Retrieved from https://www.sciencedirect.com/topics/neuroscience/methocarbamol on 2025, January 11.
[4] Carmen Pope, BPharm. Drugs.com (Updated November 2024) – Methocarbamol – Patient Tips – How it Works. Retrieved from https://www.drugs.com/tips/methocarbamol-patient-tips on 2025, January 11.
[5] Drugs.com (Updated January 2024) – Methocarbamol – Side Effects: Serious side effects of methocarbamol. Retrieved from https://www.drugs.com/sfx/methocarbamol-side-effects.html on 2025, January 11.
[6] Preston, K. L., Guarino, J. J., Kirk, W. T., & Griffiths, R. R. (1989). Evaluation of the abuse potential of methocarbamol. The Journal of pharmacology and experimental therapeutics, 248(3), 1146–1157. Retrieved from https://pubmed.ncbi.nlm.nih.gov/2703967/ on 2025, January 23
[7] Department of Health & Human Services. (n.d.). Overdose – what to do in an emergency. Better Health Channel. Retrieved from https://www.betterhealth.vic.gov.au/health/servicesandsupport/overdose-what-to-do-in-an-emergency#drug-overdose-symptoms on 2025, January 23
[8] National Library of Medicine (Updated April 2024) – DailyMed – Robaxin – Methocarbamol Injection. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=090a3d3d-92c3-4c30-a648-436461f81702 on 2025, January 11.