GHB Addiction Treatment
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Updated On : August 1, 2024
Gamma-hydroxybutyrate (GHB) is a naturally occurring compound found in the human body.[1] It functions as an analog to the GABA neurotransmitter, playing a crucial role in transmitting signals between nerve cells in the brain. In its natural state, GHB is present in small amounts and helps regulate various bodily functions, including sleep, mood, and memory.
Historically, synthetic GHB was developed for the treatment of narcolepsy and alcohol dependence, as well as for use as an anesthetic.[2] However, in recent years, the recreational use and abuse of GHB have become a public health risk due to its highly addictive nature, risk of adverse effects, and potential for severe withdrawal symptoms.
At Engage Wellness Acton, we provide services for GHB addiction treatment.
Studies indicate that GHB has a high potential for addiction, particularly due to its effects on the central nervous system.[3] GHB enhances the activity of GABA receptors in the brain, resulting in sedative, anxiolytic, and euphoric effects. Because of its euphoric effects, GHB can become highly addictive by encouraging positive reinforcement with repeated use.
The effects of this drug can be felt as early as five minutes after ingestion, peaking at 30-60 minutes after ingestion. Since there is no “hangover” effect associated with this drug, there is often repeated and frequent misuse of GHB. The immediate effects of GHB contribute to its addictive nature, further perpetuating the health risks and potential for overdose.
Regular use can lead to dependency within just weeks, and the withdrawal symptoms associated with abruptly discontinuing the drug can be severe and complicated.[4] This is another reason why many people continue to remain dependent on GHB. Users can develop a tolerance to GHB very easily, requiring higher and higher doses to achieve the same effects. Seeking professional help is necessary to safely and strategically overcome GHB addiction.
The culture around GHB use has a long history. Early use involved GHB primarily being used by bodybuilders as a performance-enhancing drug.[5] GHB gained popularity in the 80s and 90s as a recreational “club drug” used as a stimulant for sexual performance.[6] Sexual assailants also used it in combination with alcohol to form the “date rape” drug.
Due to its easy availability and near-immediate effects, GHB quickly became notorious for its abuse. GHB is colorless and odorless in its liquid form. It can also be obtained as a white powder, tablet, or capsule. GHB also has many street names, such as “Juice,” “Liquid Ecstasy,” “Liquid X,” “Georgia Home Boy,” “Mils,” “G,” “Liquid G,” and “Fantasy,” according to this journal article on GHB abuse.[7]
GHB became a “Schedule I” controlled substance in the United States under the Controlled Substances Act in 2000 due to the growing concern about its use as a recreational drug and the increase in drug overdoses and fatalities. This has led to the use of the synthetic precursor of the drug, Gamma-butyrolactone (GBL), gaining popularity since it is relatively cheap and easily available for purchase due to its use as a solvent for industrial purposes.[8] GBL is rapidly converted into GHB in the body and can produce more potent and rapid effects by weight than GHB. This potent effect makes GBL even more concerning since it can increase the risk of overdose, respiratory depression, and even death.
The misuse of GHB tends to be most prevalent among specific demographics, though it’s important to note that substance abuse can affect individuals across various age groups, genders, and socioeconomic backgrounds. Certain demographic groups, however, have been observed to have higher rates of GHB use, according to:
It’s important to recognize that GHB misuse can occur across diverse demographics, and factors such as availability, peer influence, mental health, and socio-cultural factors can all contribute to its use. Prevention efforts and targeted interventions aimed at specific demographic groups are essential to address the risks associated with GHB misuse and promote healthier choices and behaviors.
Recognizing the warning signs of GHB abuse is crucial for early intervention and GHB addiction treatment. Here are some common indicators:[9]
Recognizing these warning signs can help identify GHB abuse early, allowing for timely intervention and treatment.[10] Here, at Engage Wellness Acton, we offer treatment for GHB addiction. If you suspect someone is abusing GHB, it’s important to seek professional help to address the addiction and any associated health risks.
One notable aspect of GHB’s impact on the brain is its ability to enhance the release of dopamine, a neurotransmitter associated with pleasure and reward. This surge in dopamine levels contributes to the drug’s euphoric effects and reinforces the behavior of GHB abuse, leading to a higher risk of addiction.
When consumed in larger quantities, GHB can produce significant effects on the brain. As a central nervous system depressant, it acts by slowing down brain activity, leading to feelings of relaxation, euphoria, and sedation.
These effects are often sought after by individuals who misuse GHB recreationally. Moreover, GHB has been shown to affect the production of other neurotransmitters, such as gamma-aminobutyric acid (GABA), further contributing to its sedative and calming effects.
The troubling consequence, however, is that excessive consumption of GHB can disrupt the delicate balance of neurotransmitters in the brain, leading to adverse effects such as confusion, loss of consciousness, and respiratory depression, according to a publication in Clinical Toxicology (Philadelphia).[11]
Since withdrawal symptoms can be severe, especially when GHB is used frequently, and in high doses, dependency on this drug is an increasing concern. It is important for individuals experiencing GHB withdrawal to seek medical supervision and support to safely manage symptoms and minimize the risk of complications. Treatment for GHB addiction is available here at Engage Wellness Acton.
At Engage Wellness Acton, we understand the profound impact of gamma-hydroxybutyrate (GHB) on the body and mind. Our mission is to provide comprehensive care and support to those grappling with GHB addiction. Recognizing the high potential for addiction and the severe health risks associated with misuse, we prioritize individualized treatment plans tailored to each client’s unique needs.
Our team of experienced professionals is dedicated to guiding individuals through the challenging journey of recovery, ensuring they receive the therapeutic support necessary to safely manage withdrawal symptoms and achieve lasting sobriety.
We believe that awareness and education are crucial in GHB addiction treatment, and we are committed to offering the resources and interventions required to help individuals reclaim their lives from the grips of substance abuse. If you or a loved one is struggling with GHB addiction, we urge you to reach out for professional help. We can overcome the challenges together and work towards a healthier, drug-free future.
Engage Wellness delivers the comprehensive GHB addiction treatment you need for recovery through multiple levels of care. Our programs adapt to your stage of recovery, providing the right support and structure as you move through the healing process:
GHB addiction requires specialized treatment that addresses both its intense physical dependence and the complex social factors surrounding its use. As a drug often associated with nightlife, social pressure, and sometimes assault, GHB creates unique recovery challenges that demand a sophisticated therapeutic response.
Our comprehensive treatment approach combines proven clinical methods with personalized care to help clients break free from GHB while healing the underlying issues that drive substance use.
GHB withdrawal can be severe and potentially life-threatening, with symptoms including anxiety, tremors, and serious complications. Our team works closely with medical detox facilities to ensure safe withdrawal management. We carefully monitor clients during the transition to treatment and provide 24/7 support during our day treatment program to address any post-acute withdrawal symptoms.
Many people seeking treatment for GHB have experienced trauma related to its use. Our program includes specialized trauma therapy through EMDR and other evidence-based approaches, creating safe spaces to address these sensitive issues with trained clinicians who understand the connection between trauma and substance use.
Many clients struggle with both GHB and alcohol use, as they often go hand in hand in party settings. Our treatment program addresses polysubstance use through integrated care that tackles the unique challenges of multiple addictions. We help clients understand the heightened risks of combining substances while developing comprehensive recovery strategies.
[1] Tomlinson, M. F., Brown, M., & Hoaken, P. N. (2016). Recreational drug use and human aggressive behavior: A comprehensive review since 2003. Aggression and Violent Behavior, 27, 9–29. https://doi.org/10.1016/j.avb.2016.02.004 on February 13, 2025
[2] Caputo, F., Vignoli, T., Maremmani, I., Bernardi, M., & Zoli, G. (2009). Gamma hydroxybutyric acid (GHB) for the treatment of alcohol dependence: a review. International journal of environmental research and public health, 6(6), 1917–1929. https://doi.org/10.3390/ijerph6061917 on February 13, 2025
[3] GHB – Gamma-Hydroxybutyric Acid | Get Smart About Drugs. (n.d.). Www.getsmartaboutdrugs.gov. https://www.getsmartaboutdrugs.gov/drugs/ghb-gamma-hydroxybutyric-acid on February 13, 2025
[4] Dyer, J. E., Roth, B., & Hyma, B. A. (2001). Gamma-hydroxybutyrate withdrawal syndrome. Annals of Emergency Medicine, 37(2), 147–153. https://pubmed.ncbi.nlm.nih.gov/11174231/ on February 13, 2025
[5] Giorgetti, A., Busardò, F. P., & Giorgetti, R. (2022). Toxicological characterization of GHB as a Performance-Enhancing Drug. Frontiers in Psychiatry, 13. https://doi.org/10.3389/fpsyt.2022.846983 on February 13, 2025
[6] Busardò, F. P., & Jones, A. W. (2015). GHB pharmacology and toxicology: acute intoxication, concentrations in blood and urine in forensic cases and treatment of the withdrawal syndrome. Current neuropharmacology, 13(1), 47–70. https://doi.org/10.2174/1570159X13666141210215423 on February 13, 2025
[7, 10] Marinelli, E., Beck, R., Malvasi, A., Lo Faro, A. F., & Zaami, S. (2020). Gamma-hydroxybutyrate abuse: pharmacology and poisoning and withdrawal management. Archives of Industrial Hygiene and Toxicology, 71(1), 19–26. https://pmc.ncbi.nlm.nih.gov/articles/PMC7837237/ on February 15, 2025
[8] Palmer, R. B. (2004). ??-Butyrolactone and 1,4-Butanediol. Toxicological Reviews, 23(1), 21–31. https://pubmed.ncbi.nlm.nih.gov/15298490/ on February 13, 2025
[9] Department of Health & Human Services. (n.d.). GHB. Better Health Channel. https://www.betterhealth.vic.gov.au/health/healthyliving/GHB#short-term-effects-of-ghb on February 13, 2025
[11] Schep, L. J., Knudsen, K., Slaughter, R. J., Vale, J. A., & Mégarbane, B. (2012). The clinical toxicology of gamma-hydroxybutyrate, gamma-butyrolactone and 1,4-butanediol. Clinical Toxicology, 50(6), 458–470. https://pubmed.ncbi.nlm.nih.gov/22746383/ on February 13, 2025